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    Prenatal Diagnosis

    Checkup includes some specialised blood tests, preferably carried out in the beginning of each pregnancy or right before it. If you follow an IVF cycle, they should ideally be carried out before the cycle starts, because in some of those tests, results are ready after several days. Although some couples feel “tired” after the numerous tests they have undergone, it must be stressed that prenatal tests as listed below may prevent conditions with severe consequences. Necessary – recommemnded female tests are: • Full blood count: if you haven’t had this test recently, it is recommended that you repeat it. Full blood count shows whether you have anemia (low hematocrit, low iron), in order to regulate the problem before you get pregnant. It also shows whether there are platelet disorders (blood clotting).

    • Globulin electrophoresis (Hb): Thalassemia stigma is detected.
    • Rubella IgG-IgM: nowadays, it is a rare disease, because everybody is vaccinated. However, if you aren’t immunised against rubella, vaccination is recommended. In case a woman is infected during the 1st trimester of her pregnancy, rubella causes to the embryo abnormalities, such as ocular damages, deafness, cardiac damages and mental retardation.
    • Cytomegalovirus (CMV IgG-IgM): in case this test gives positive results, the IVF cycle must be postponed until the disease passes off. CMV disease causes enlargement of the baby’s liver and spleen, microcephaly and psychokinetic retardation (similar to the toxoplasmosis symptoms). It is a severe disease, with no cure.
    • Toxoplasmosis (Toxo IgG-IgM): in case this test gives positive results, the IVF cycle must be postponed until the disease passes off. Its treatment includes antibiotics. The disease is transmitted to pregnant women by an infected cat. In case a woman is infected during the 1st trimester of her pregnancy, toxoplasma may lead to intrauterine death or to a baby born with congenital toxoplasmosis. The most characteristic symptoms of the disease are microcephaly and psychokinetic retardation. Otherwise, in case she is infected in the 3rd trimester, an asymptomatic baby or a baby with chorioretinitis is born.
    • Thyroid hormones (TSH, T4): Thyroiditis is common among women. Unregulated thyroiditis is responsible for miscarriages.
    • Hepatitis B (HbsAg) and Hepatitis C (HCV): although these forms of hepatitis are rare, sometimes they are detected and have severe health consequences.
    • Syphilis (VDRL)
    • AIDS (HIV I-II) These tests are deemed necessary for the safety of your embryo (and subsequently baby), for other couples’ safety, as well as for the safety of people working at “gennima”. Results of the 3 aforementioned tests must be of the past year. If a test gives positive results, on the one hand we recommend that you consult specialists and on the other hand, the embryos that will be formed will be cultured separately.
    • Cystic Fibrosis (CFTR): this test includes all known Cystic Fibrosis gene mutations (please read more about Cystic Fibrosis in the Appendix).
    • Cardiogram: it is necessary in case you proceed with an IVF cycle, as you will undergo a very mild sedation during oocyte retrieval.

    Necessary – recommended male tests are:
    • Hepatitis B (HbsAg) and Hepatitis C (HCV): although these types of hepatitis are rare, sometimes they are detected and have severe health consequences.
    • Syphilis (VDRL)
    • AIDS (HIV I-II) These tests are deemed necessary for the safety of your embryo (and subsequently baby), for other couples’ safety, as well as for the safety of people working at “gennima”. Results of the 3 aforementioned tests must be of the past year.

    If a test gives positive results, on the one hand we recommend that you consult specialists and on the other hand, the embryos that will be formed, will be cultured separately.
    ​• Globulin electrophoresis (Hb): In case the woman has thalassemia stigma or a marginal result.


    Gennima | Gynaecology & Reproduction Center

    346 Kifisias Avenue, 15233 Chalandri - Athens, Hellas
    +30 210 68 16 100
    +30 210 68 30 321 (fax)
    info[at]gennima[.]eu

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