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    Safety

    Researchers have been focusing on children born following PGD, in order to verify that they are healthy and that the method does not affect the health of the children to be born.
    PGD is being used for 20 years now. There are multiple clinical studies reassuring that the PGD method itself doesn’t harm embryos and that children born following PGD aren’t different from those born by means of classic IVF (e.g. congenital abnormalities among these children are being statistically analysed). The one (1) cell removed from the 8-cell embryo does not harm the preimplantation embryo development towards a healthy baby.
    Please find below a recent study:
    ‘Report on a consecutive series of 581 children born after blastomere biopsy for preimplantation genetic diagnosis’.
    Human Reproduction, Vol.25, No.1 pp. 275 - 282, 2010.
    http://humrep.oxfordjournals.org/cgi/reprint/25/1/275

    ‘Children born after preimplantation genetic diagnosis show no increase in congenital abnormalities’.
    Human Reproduction, Vol.25, No.1 pp. 6 - 8, 2010.
    http://humrep.oxfordjournals.org/cgi/reprint/25/1/6

    This is the study with the largest number of participants, which has started in 1992, in Belgium, and has collected data until 2005, involving a population of 600 children born after PGD. This study hasn’t detected any statistically significant difference between children born after PGD and those born without PGD. The most important risk factor was preterm birth and low birth weight in multiple pregnancy. The study concludes that PGD is safe, when performed, of course, by experienced scientists, who apply the appropriate technique.

    The European Society for Human Reproduction and Embryology (ESHRE), where Greek doctors participate as well, conveys its position concerning PGS, especially with regards to issues of ethics, with the statement below:
    ESHRE position paper – Ethics and Law Task Force
    http://www.eshre.eu/~/media/emagic%20files/SIGs/Ethics%20and%20Law/Task%20Forces/Task%20Force%205.pdf


    Gennima | Gynaecology & Reproduction Center

    346 Kifisias Avenue, 15233 Chalandri - Athens, Hellas
    +30 210 68 16 100
    +30 210 68 30 321 (fax)
    info[at]gennima[.]eu

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