In Vitro Fertilisation Protocols
There are 2 basic ovarian stimulation protocols, the “long” one and the “short” one, as well as many variations, selected depending on the hormone profile, the clinical profile and the history of each couple. Medication is administered in the form of subcutaneous injections.
In general, the long protocol includes GnRH-agonists, such as ARVEKAP (triptorelin) and DARONDA (leuprorelin) and begins with ovarian suppression, aiming to regulate the IVF cycle, approximately on the 21st day of the menstrual cycle. The first day of the cycle is considered to be the first day of your period.
After having your period, you must undergo a transvaginal ultrasound and a blood test to check your hormones. This is necessary, in order to detect whether suppression has been achieved. Then, the medication for stimulation is administered, helping the ovaries produce many follicles. Every 2 or 3 days, you must have a blood test and a transvaginal ultrasound; with the blood test we monitor hormone levels and with the ultrasound we monitor follicular progress.
The short protocol includes GnRH – antagonists, such as ORGALUTRAN (genirelix) and CETROTIDE (cetrorelix) and starts on the 2nd or 3rd day of your menstrual cycle. The first day of the cycle is considered to be the first day of your period.
On the 2nd day, you have a transvaginal ultrasound and a hormone blood test. Then, the stimulation drug is administered, while the medication for suppression starts on the 6th or 7th day approximately. As in the long protocol, a transvaginal ultrasound and hormone control must be carried out every 2 or 3 days.