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    Clomiphene ovulation induction

    Clomiphene (commercial brand in Greece: Serpafar or Clomid) is a widely-used medication for ovulation induction in women who do not ovulate on their own (due to polycystic ovaries etc.). Clomiphene has been used for many years by millions of women worldwide and has presented no major side effects (when used according to the doctor’s recommendations).
    ​It is a non-steroidal drug that interacts with the estrogen receptor at the hypothalamus (selective estrogen receptor modulator: SERM). This way clomiphene raises FSH levels and induces ovulation. However, clomiphene itself is not a hormone.

    Clomiphene is suitable for…
    Mostly for women with irregular periods or polycystic ovaries.
    Before trying for a baby using clomiphene for ovulation induction, all couples should visit a fertility expert for a fertility consultation. The doctor might suggest some tests: blood tests, ultrasound scan, semen analysis etc.

    How is it used?

    Clomiphene is administered orally (pills) so it is really easy to use. Also, it doesn’t cost much. The usual protocol is 2 tablets a day (50mg/tablet twice a day) starting on day 2 or 3 of a woman’s cycle for 5 days. Day 1 of your cycle is when starting bleeding with red blood (not pink or brown). Ideally, the doctor should check that clomiphene actually works (that it actually does induce ovulation) by ultrasound scan and blood test. In some cases, clomiphene may induce multiple ovulation (2 or more eggs). Then there is a 10% chance of twin pregnancy (triplets are rare).

    How often can a woman take clomiphene?

    As a rule, clomiphene should be used in up to 6 cycles. If you do not succeed to get pregnant after 6 cycles with clomiphene, then fertility experts suggest that you do more tests and try alternative ovulation methods (alternative medication to induce ovulation, IUI or IVF).

    Clomiphene side effects and risks

    The most common side-effects of clomiphene (about 10%) are hot flashes, headaches, abdominal pain or bloating and blurred vision. In some clinical studies, long term effects have been mentioned when using clomiphene for a long period of time, but these have not been confirmed.

    Clomiphene babies are healthy

    Babies born following clomiphene use are healthy and no different than babies born without it. Use of clomiphene does not increase miscarriages.

    Gennima | Gynaecology & Reproduction Center

    346 Kifisias Avenue, 15233 Chalandri - Athens, Hellas
    +30 210 68 16 100
    +30 210 68 30 321 (fax)